Ordering Test Kits and Test Analyses

Yes. Requests for overnight kit shipments must be made before 2:00PM EST. Please contact MNG by phone at (+1) 678-225-0222 and a customer service representative will be happy to assist you.  If you are a provider located outside the U.S. and do not have an existing MNG account, please contact us at (+1) 844-664-8378 or [email protected] for additional information regarding MNG service levels including: test offerings, request forms, kits, payment options, etc.

MNG accepts samples Monday through Saturday from 8:00AM-5:00PM EST, except on the following US national holidays: New Year’s Day (January 1), Memorial Day (last Monday in May), Independence Day (July 4), Labor Day (First Monday in September), Thanksgiving (fourth Thursday in November), and Christmas (December 25).  If you are a provider located outside the U.S. and do not have an existing MNG account, please contact us at (+1) 844-664-8378 or [email protected] for additional information regarding MNG service levels including:  test offerings, request forms, kits, payment options, etc.

Healthcare professionals may order a custom NGS panel. Please contact us by phone or email to discuss the genes of your custom panel and one can be developed.

Client Requested Cancellations 

Client requested cancellation of testing, after sample processing and analysis has begun at MNG, is based on the published test turnaround times, as follows:

Cancellations by MNG Labs 

MNG Laboratories reserves the right to cancel any test given appropriate reasoning. Cancellation of testing by MNG Laboratories may be due to:

• Lack of sufficient sample (quantity not sufficient-QNS) for the requested testing. Cancellation will occur as soon as the quantity is verified as not sufficient.
• Sample quality, as determined by the laboratory, is below the required quality by the test process to be employed.
• Unacceptable sample type received for requested testing.
• A sample received in a compromised state that will affect the outcome of the results (i.e. thawed if it is to be received frozen, severely clotted, improper storage conditions, etc.)
• Non-payment/non-communication with the laboratory regarding billing or clarification of information.

Yes. MNG offers STAT service for an additional charge. Please complete the STAT Test Request Form and submit it with your test order forms. STAT additions to testing already in process follow the same timeline as our Cancellation Policy. 

MNG Laboratories will ensure any STAT orders meet the stated deadline, or the STAT fee will be waived. 

*Please note that this option is not available for Familial Variant Testing, ENZ01, ENZ06, MET22, or MET25
 

MNG can test parents/family members for Known Familial Mutation Analysis, mitochondrial DNA testing, and genetic carrier screening. Please fill out the applicable requisition form on our Forms page, in the “Test Request Forms” section.

Please contact an MNG Genetic Coordinator to discuss the feasibility of prenatal testing prior to submitting a sample. Genetic Coordinators can be reached at 678-225-0222 or [email protected].

MNG can only accept extracted DNA for prenatal testing. Extracted DNA may be sourced from amniotic fluid, cultured amniotic fluid, chorionic villi, cultured chorionic villi, products of conception (POC), cultured POC, or fetal tissue. MNG is not able to maintain or grow cultures, extract from prenatal specimens, or perform maternal cell contamination (MCC) studies. Culturing, extraction, and MCC must be performed at an outside facility. A negative MCC result (<10%) must accompany the prenatal sample.

Please contact an MNG Genetic Coordinator to discuss the feasibility of testing on cord blood prior to submitting a sample. Genetic Coordinators can be reached at 678-225-0222 or [email protected].

MNG can accept cord blood for testing. At least 2 mL of cord blood in an EDTA vacutainer is required.

MNG does not perform maternal cell contamination (MCC) studies. A negative MCC result (<10%) must accompany the cord blood sample.

The CSF Collection Instruction Sheet on our Forms page, under the “Specimen Collection and Processing Form” section.

MNG can test blood, fibroblasts, skin, and muscle samples for RNA sequencing. Please call us prior to submitting any samples as we supply a blood collection tube specific for RNA sequencing. We will help you to determine the best sample type for your patient’s clinical presentation and genes of interest as RNA expression varies across tissue types.

MNG Laboratories works with institutional and international clients and bills directly for our services. Suggested CPT codes are provided in the test directory to help clients who wish to bill insurance; however, MNG does not bill insurance companies directly at this time.

Simply complete and submit an initial test requisition and an institutional billing account will be established automatically. The billing information section must be completed in full in order to set up an account. MNG Laboratories is not a direct-to-consumer laboratory; therefore, accounts will only be created for licensed physicians, clinics, or hospitals.  If you are a provider located outside the U.S. and do not have an existing MNG account, please contact us at (+1) 844-664-8378 or [email protected] for additional information regarding MNG service levels including: test offerings, request forms, kits, payment options, etc.

Tax ID: 47-3459045 NPI: 1447436514

Blood in an EDTA tube is typically stable for 7-10 days at room temperature and rocking. If there are noticeable clots in the tube or the blood is badly hemolyzed, MNG will not be able to isolate usable quality DNA, and a new sample will be required. Blood specimens should be shipped overnight in a secure container at room temperature. Please do not freeze blood samples.

The sample retention policy applies to both new and stored samples, and is as follows:

• DNA Analysis (Excluding Whole Exome Sequencing and Whole Genome Sequencing):  Extracted DNA will be retained for 60 days.
• Whole Exome Sequencing and Whole Genome Sequencing: Extracted DNA will be retained for 2 years.
• RNA Sequencing or Transcriptome Analysis: Extracted RNA will be held for 2 years.
• Neurochemistry Analysis: Cerebrospinal fluid (CSF) will be retained for 1 year.
• Tissue, slides, tissue blocks: Includes but is not limited to frozen tissue, slides, and formalin fixed paraffin embedded tissue blocks. Specimens will be retained for 20 years.

After testing is performed, the laboratory cannot guarantee that there will be residual sample remaining for any add-on testing. If add-on or additional testing is required, MNG encourages that you reach out to client services prior to submitting an order.

Samples from the state of New York require consent for the laboratory to retain the specimen past 60 days. 

MNG Laboratories guarantees 100% coverage of known pathogenic variants in genes listed in our next-generation sequencing panels. Disease causing variants are confirmed using alternative technology as well as areas of low coverage. The target is 300-fold average coverage, and we guarantee 135-fold coverage for NGS panels. Minimum coverage is 10-fold; however, if any variants are suspected, alternative methodologies is used to confirm these findings. For deletion/duplication analysis in NGS panels, known pathogenic variants have a sensitivity of single nucleotide detection, and for any other gene we can detect larger deletions and duplications of 10 exons or greater. For whole exome sequencing, please see our MNG Exome™ page describing coverage, methodology, and specifications. For whole genome coverage information, please see the MNGenome® page for everything included with genome analysis.

MNG uses targeted PCR followed by Sanger or NGS to confirm all pathogenic and likely pathogenic variants, and to assist in evaluating variants found in regions not adequately covered to quality control specifications.